As of 2023, the best AI text-to-speech software is subjective and varies based on individual needs and preferences. However, some popular options include eSpeak, MurfAI, and Natural Reader. eSpeak is a free, open-source software with a range of customizable voices and supports multiple languages. MurfAI is designed for businesses and aims to produce high-quality, natural-sounding speech. Natural Reader is known for its easy-to-use interface and stellar results, with both free and paid plans available. Other notable text-to-speech tools include LovoAI, Speechify, and Genny by LOVO. Ultimately, the best software depends on factors such as the desired output quality, ease of use, and specific features needed.